Lysine acetylation targets protein complexes and co-regulates major cellular functions
PFAM Sites
| Site | Peptides | |
|---|---|---|
| None | 1243 | |
| Thiolase_N | 13 | |
| GTP_EFTU | 13 | |
| RRM_1 | 12 | |
| Thioredoxin | 12 | |
| Abhydrolase_6 | 10 | |
| adh_short | 8 | |
| Pro_isomerase | 8 | |
| TCTP | 8 | |
| Iso_dh | 7 | |
| Aminotran_1_2 | 7 | |
| Proteasome | 6 | |
| FKBP_C | 6 | |
| Pyr_redox_2 | 6 | |
| GST_C | 5 | |
| KAT11 | 5 | |
| Histone | 5 | |
| Thioredoxin_6 | 5 | |
| Ldh_1_C | 5 | |
| NDK | 5 | |
| Cofilin_ADF | 5 | |
| DAO | 4 | |
| ATP-synt_ab_C | 4 | |
| Tubulin | 4 | |
| LTD | 4 | |
| Pkinase | 4 | |
| DEAD | 4 | |
| tRNA-synt_1c | 4 | |
| adh_short_C2 | 4 | |
| UQ_con | 4 | |
| Ribosomal_L1 | 4 | |
| 14-3-3 | 4 | |
| Catalase | 4 | |
| TBCA | 4 | |
| Ras | 4 | |
| Peptidase_M24 | 4 | |
| ACBP | 4 | |
| Peptidase_M16_C | 3 | |
| Acyl-CoA_dh_1 | 3 | |
| HATPase_c | 3 | |
| ATP-synt | 3 | |
| Lyase_1 | 3 | |
| ubiquitin | 3 | |
| EF_hand_5 | 3 | |
| Ribosomal_L12 | 3 | |
| GTP_EFTU_D3 | 3 | |
| PBP | 3 | |
| Ribosomal_S13_N | 3 | |
| DnaJ | 3 | |
| GST_N | 3 | |
| Aldo_ket_red | 3 | |
| PP-binding | 3 | |
| Transketolase_N | 3 | |
| 2-oxoacid_dh | 3 | |
| Ribosomal_S27 | 3 | |
| ETF | 2 | |
| HGTP_anticodon | 2 | |
| DUF902 | 2 | |
| p450 | 2 | |
| Cytochrom_C | 2 | |
| MAM33 | 2 | |
| Gp_dh_C | 2 | |
| Acyl_transf_1 | 2 | |
| 3HCDH_N | 2 | |
| 3HCDH | 2 | |
| MADF_DNA_bdg | 2 | |
| Ribosomal_L30_N | 2 | |
| FERM_C | 2 | |
| Carb_anhydrase | 2 | |
| ECH_C | 2 | |
| HMG_box | 2 | |
| Myosin_head | 2 | |
| LSM | 2 | |
| Lipocalin | 2 | |
| Succ_DH_flav_C | 2 | |
| Ligase_CoA | 2 | |
| Linker_histone | 2 | |
| RS4NT | 2 | |
| KH_2 | 2 | |
| Malic_M | 2 | |
| Cpn10 | 2 | |
| Sod_Fe_C | 2 | |
| CPSase_L_D2 | 2 | |
| Acetyltransf_7 | 2 | |
| Enolase_C | 2 | |
| Ribosomal_L6 | 2 | |
| SSB | 2 | |
| Pyr_redox_dim | 2 | |
| Glutaredoxin | 2 | |
| tRNA_anti | 2 | |
| Helicase_C_2 | 1 | |
| UFC1 | 1 | |
| SHMT | 1 | |
| Ribosomal_L6e_N | 1 | |
| ATP-synt_ab_N | 1 | |
| Acyl-CoA_dh_N | 1 | |
| Ribosomal_L22 | 1 | |
| GARS_A | 1 | |
| Macro | 1 | |
| CH | 1 | |
| 2-Hacid_dh_C | 1 | |
| GTP_EFTU_D2 | 1 | |
| EFG_IV | 1 | |
| Vps39_1 | 1 | |
| HD_3 | 1 | |
| Ham1p_like | 1 | |
| Ribosomal_L30 | 1 | |
| ZZ | 1 | |
| Metallophos | 1 | |
| UBA | 1 | |
| Acyl-CoA_dh_M | 1 | |
| ADH_N | 1 | |
| tRNA-synt_2b | 1 | |
| MIF4G_like_2 | 1 | |
| ELFV_dehydrog | 1 | |
| Gln-synt_C | 1 | |
| NOSIC | 1 | |
| Sec23_trunk | 1 | |
| RNase_PH_C | 1 | |
| Myb_DNA-bind_4 | 1 | |
| Ribos_L4_asso_C | 1 | |
| G6PD_N | 1 | |
| CS | 1 | |
| DNA_gyraseB | 1 | |
| Ribosomal_L5 | 1 | |
| SSrecog | 1 | |
| Rtt106 | 1 | |
| Gp_dh_N | 1 | |
| SAM_1 | 1 | |
| AlaDh_PNT_N | 1 | |
| PNP_UDP_1 | 1 | |
| TUDOR | 1 | |
| Fibrillarin | 1 | |
| Ribosomal_S5 | 1 | |
| UDPG_MGDP_dh_N | 1 | |
| zf-CCHC | 1 | |
| FERM_N | 1 | |
| FERM_M | 1 | |
| Alpha-2-MRAP_N | 1 | |
| Ribosomal_L7Ae | 1 | |
| S1 | 1 | |
| CYTH | 1 | |
| zf-C2H2_4 | 1 | |
| Chromo | 1 | |
| ABC_tran | 1 | |
| Cse1 | 1 | |
| MBD | 1 | |
| Cys_Met_Meta_PP | 1 | |
| Ribosomal_S6 | 1 | |
| zf-AD | 1 | |
| Kinesin | 1 | |
| zf-C2H2_6 | 1 | |
| Homeobox | 1 | |
| 2OG-FeII_Oxy | 1 | |
| Clathrin_H_link | 1 | |
| MMS1_N | 1 | |
| ATP-grasp_2 | 1 | |
| Tubulin_C | 1 | |
| Peptidase_M17 | 1 | |
| Transket_pyr | 1 | |
| HMA | 1 | |
| ARID | 1 | |
| Abhydrolase_2 | 1 | |
| PH | 1 | |
| PCNA_N | 1 | |
| Peptidase_S8 | 1 | |
| NAD_binding_10 | 1 | |
| Cyt-b5 | 1 | |
| SRP_SPB | 1 | |
| SRP54_N | 1 | |
| RNA_pol_A_bac | 1 | |
| PC4 | 1 | |
| BRO1 | 1 | |
| BAF | 1 | |
| PRK | 1 | |
| dsrm | 1 | |
| Ribosomal_L2_C | 1 | |
| PP28 | 1 | |
| DUF836 | 1 | |
| COX5A | 1 | |
| BAH | 1 | |
| Hat1_N | 1 | |
| AdoHcyase | 1 | |
| zf-CDGSH | 1 | |
| Sod_Fe_N | 1 | |
| WW | 1 | |
| Arrestin_C | 1 | |
| DEK_C | 1 | |
| DUF1897 | 1 | |
| DUF543 | 1 | |
| Ribosomal_S7 | 1 | |
| Slu7 | 1 | |
| DUF814 | 1 | |
| Filamin | 1 | |
| HLH | 1 | |
| Vps5 | 1 | |
| Peptidase_C12 | 1 | |
| PGM_PMM_II | 1 | |
| Rho_GDI | 1 | |
| DHFR_1 | 1 | |
| ATP-cone | 1 | |
| GST_N_3 | 1 | |
| Rep-A_N | 1 | |
| Nucleoporin_N | 1 |
PFAM Domains
| Domain | Peptides | |
|---|---|---|
| None | 173 | |
| RRM_1 | 13 | |
| Pkinase | 9 | |
| DEAD | 7 | |
| Proteasome | 6 | |
| Proteasome_A_N | 6 | |
| Histone | 6 | |
| Acyl-CoA_dh_M | 4 | |
| HATPase_c | 4 | |
| GST_C | 4 | |
| PHD | 4 | |
| UQ_con | 4 | |
| adh_short | 3 | |
| Peptidase_M16_C | 3 | |
| Acyl-CoA_dh_1 | 3 | |
| GST_N | 3 | |
| Tubulin | 3 | |
| Tubulin_C | 3 | |
| CPSase_L_D2 | 3 | |
| CPSase_L_chain | 3 | |
| GTP_EFTU | 3 | |
| GTP_EFTU_D2 | 3 | |
| UBA | 3 | |
| Iso_dh | 3 | |
| ubiquitin | 3 | |
| zf-H2C2_2 | 3 | |
| tRNA_anti | 3 | |
| Ribosomal_L7Ae | 3 | |
| HMG_box | 3 | |
| Chromo | 3 | |
| FKBP_C | 3 | |
| Peptidase_M24 | 3 | |
| ATP-synt_ab_C | 2 | |
| ATP-synt_ab_N | 2 | |
| Acyl-CoA_dh_N | 2 | |
| HGTP_anticodon | 2 | |
| Rep_fac_C | 2 | |
| SAM_1 | 2 | |
| AIRS_C | 2 | |
| AIRS | 2 | |
| Pro_isomerase | 2 | |
| Pyr_redox_2 | 2 | |
| S1 | 2 | |
| Ribosomal_L30 | 2 | |
| Bromodomain | 2 | |
| ADH_N | 2 | |
| tRNA-synt_2b | 2 | |
| p450 | 2 | |
| GST_N_3 | 2 | |
| Homeobox | 2 | |
| DUF4009 | 2 | |
| zf-CDGSH | 2 | |
| EF_hand_5 | 2 | |
| Cyclin_N | 2 | |
| Cyclin_C | 2 | |
| CS | 2 | |
| PP-binding | 2 | |
| GTP_EFTU_D3 | 2 | |
| Rtt106 | 2 | |
| BTB | 2 | |
| zf-HC5HC2H_2 | 2 | |
| DnaJ | 2 | |
| DnaJ_C | 2 | |
| tRNA-synt_1c | 2 | |
| tRNA-synt_1c_C | 2 | |
| RRM_6 | 2 | |
| MADF_DNA_bdg | 2 | |
| zf-C2H2_4 | 2 | |
| Dynein_heavy | 2 | |
| AAA_9 | 2 | |
| AAA_8 | 2 | |
| MT | 2 | |
| Thioredoxin | 2 | |
| Thioredoxin_6 | 2 | |
| Aminotran_1_2 | 2 | |
| Ribosomal_L1 | 2 | |
| HLH | 2 | |
| zf-C2H2 | 2 | |
| Kinesin | 2 | |
| Cyt-b5 | 2 | |
| MBD | 2 | |
| Ras | 2 | |
| Ligase_CoA | 2 | |
| AAA_5 | 2 | |
| Ldh_1_C | 2 | |
| ACBP | 2 | |
| Biotin_carb_C | 2 | |
| Biotin_lipoyl | 2 | |
| Helicase_C_2 | 1 | |
| UFC1 | 1 | |
| Apc3 | 1 | |
| WW | 1 | |
| SHMT | 1 | |
| Thiolase_N | 1 | |
| Thiolase_C | 1 | |
| ETF | 1 | |
| DAO | 1 | |
| GCV_T | 1 | |
| GCV_T_C | 1 | |
| Ribosomal_L6e_N | 1 | |
| OMPdecase | 1 | |
| Pribosyltran | 1 | |
| SLIDE | 1 | |
| HAND | 1 | |
| AAA_33 | 1 | |
| ATP-synt | 1 | |
| RRM_5 | 1 | |
| Nefa_Nip30_N | 1 | |
| Ribosomal_L22 | 1 | |
| LTD | 1 | |
| CXC | 1 | |
| Kelch_3 | 1 | |
| GARS_A | 1 | |
| Formyl_trans_N | 1 | |
| GARS_N | 1 | |
| GARS_C | 1 | |
| Macro | 1 | |
| CRM1_C | 1 | |
| GATase | 1 | |
| OTCace_N | 1 | |
| CPSase_sm_chain | 1 | |
| CPSase_L_D3 | 1 | |
| OTCace | 1 | |
| MGS | 1 | |
| Amidohydro_1 | 1 | |
| CH | 1 | |
| tRNA_SAD | 1 | |
| 2-Hacid_dh_C | 1 | |
| EFG_IV | 1 | |
| EFG_C | 1 | |
| Vps39_2 | 1 | |
| Vps39_1 | 1 | |
| HD_3 | 1 | |
| SH3_1 | 1 | |
| TPP_enzyme_N | 1 | |
| TPP_enzyme_M | 1 | |
| TPP_enzyme_C | 1 | |
| Ham1p_like | 1 | |
| KAT11 | 1 | |
| KIX | 1 | |
| DUF902 | 1 | |
| ZZ | 1 | |
| Metallophos | 1 | |
| zf-MaoC | 1 | |
| AAA_18 | 1 | |
| EF1_GNE | 1 | |
| EF-1_beta_acid | 1 | |
| Lyase_1 | 1 | |
| FumaraseC_C | 1 | |
| PolyA_pol_RNAbd | 1 | |
| PolyA_pol | 1 | |
| MIF4G_like_2 | 1 | |
| MIF4G_like | 1 | |
| HIT | 1 | |
| ELFV_dehydrog | 1 | |
| ELFV_dehydrog_N | 1 | |
| NUC173 | 1 | |
| UBX | 1 | |
| BP28CT | 1 | |
| Gln-synt_C | 1 | |
| Gln-synt_N | 1 | |
| Ets | 1 | |
| SAM_PNT | 1 | |
| SRF-TF | 1 | |
| NOSIC | 1 | |
| NOP5NT | 1 | |
| Sec23_trunk | 1 | |
| Sec23_helical | 1 | |
| Sec23_BS | 1 | |
| zf-Sec23_Sec24 | 1 | |
| Gelsolin | 1 | |
| NGP1NT | 1 | |
| AAA_34 | 1 | |
| Helicase_C_4 | 1 | |
| CUT | 1 | |
| Cytochrom_C | 1 | |
| RNase_PH | 1 | |
| RNase_PH_C | 1 | |
| PNPase | 1 | |
| Myb_DNA-bind_4 | 1 | |
| Ribos_L4_asso_C | 1 | |
| zf-AD | 1 | |
| G6PD_C | 1 | |
| G6PD_N | 1 | |
| Med13_N | 1 | |
| Ribosomal_L12 | 1 | |
| SM-ATX | 1 | |
| LsmAD | 1 | |
| RFC1 | 1 | |
| DNA_gyraseB | 1 | |
| Med26 | 1 | |
| TFIIS_M | 1 | |
| SPOC | 1 | |
| BRK | 1 | |
| Ribosomal_L5_C | 1 | |
| Ribosomal_L5 | 1 | |
| PBP | 1 | |
| Abhydrolase_6 | 1 | |
| tRNA_int_end_N2 | 1 | |
| PWWP | 1 | |
| PK_C | 1 | |
| MAM33 | 1 | |
| SSrecog | 1 | |
| Pyrophosphatase | 1 | |
| Acetyltransf_13 | 1 | |
| zf-C2H2_3 | 1 | |
| Peptidase_C14 | 1 | |
| Gp_dh_C | 1 | |
| Gp_dh_N | 1 | |
| SAM_2 | 1 | |
| AlaDh_PNT_C | 1 | |
| AlaDh_PNT_N | 1 | |
| PNP_UDP_1 | 1 | |
| Ribosomal_S13_N | 1 | |
| Ribosomal_S15 | 1 | |
| DnaJ_CXXCXGXG | 1 | |
| Acyl_transf_1 | 1 | |
| Transket_pyr | 1 | |
| TUDOR | 1 | |
| 3HCDH_N | 1 | |
| 3HCDH | 1 | |
| KH_3 | 1 | |
| adh_short_C2 | 1 | |
| Fibrillarin | 1 | |
| Plus-3 | 1 | |
| Ribosomal_S5 | 1 | |
| Ribosomal_S5_C | 1 | |
| UDPG_MGDP_dh_N | 1 | |
| UDPG_MGDP_dh_C | 1 | |
| UDPG_MGDP_dh | 1 | |
| UBA_e1_C | 1 | |
| UBA_e1_thiolCys | 1 | |
| Ribosomal_L30_N | 1 | |
| RHD | 1 | |
| TIG | 1 | |
| Rho_Binding | 1 | |
| zf-CCHC | 1 | |
| DUF4217 | 1 | |
| IF-2 | 1 | |
| EF1G | 1 | |
| zf-HC5HC2H | 1 | |
| Aldo_ket_red | 1 | |
| FERM_C | 1 | |
| FERM_M | 1 | |
| FERM_N | 1 | |
| Alpha-2-MRAP_C | 1 | |
| Alpha-2-MRAP_N | 1 | |
| SYF2 | 1 | |
| CHDCT2 | 1 | |
| DUF1086 | 1 | |
| CHDNT | 1 | |
| DUF1087 | 1 | |
| zf-met | 1 | |
| Carb_anhydrase | 1 | |
| NOPS | 1 | |
| RhoGAP | 1 | |
| AIRC | 1 | |
| ECH_C | 1 | |
| GYF | 1 | |
| ING | 1 | |
| NUDIX | 1 | |
| CDC37_M | 1 | |
| CDC37_N | 1 | |
| CDC37_C | 1 | |
| SRP72 | 1 | |
| Lactamase_B | 1 | |
| NFRKB_winged | 1 | |
| DBINO | 1 | |
| Myosin_head | 1 | |
| Myosin_N | 1 | |
| TCTP | 1 | |
| EAF | 1 | |
| CYTH | 1 | |
| Epimerase_Csub | 1 | |
| Pkinase_Tyr | 1 | |
| PBD | 1 | |
| 14-3-3 | 1 | |
| SRP40_C | 1 | |
| UCH37_bd | 1 | |
| Chromo_shadow | 1 | |
| ABC_tran | 1 | |
| Fer4 | 1 | |
| Catalase | 1 | |
| AhpC-TSA | 1 | |
| 1-cysPrx_C | 1 | |
| IBN_N | 1 | |
| Cse1 | 1 | |
| Methyltransf_11 | 1 | |
| LSM | 1 | |
| Cys_Met_Meta_PP | 1 | |
| Ribosomal_S6 | 1 | |
| Ku_PK_bind | 1 | |
| Lipocalin | 1 | |
| zf-C3Hc3H | 1 | |
| TBCA | 1 | |
| La | 1 | |
| RRM_3 | 1 | |
| zf-C2H2_6 | 1 | |
| eIF3_N | 1 | |
| 2OG-FeII_Oxy | 1 | |
| Clathrin_H_link | 1 | |
| Clathrin-link | 1 | |
| Succ_DH_flav_C | 1 | |
| CoA_binding | 1 | |
| MMS1_N | 1 | |
| HTH_Tnp_Tc5 | 1 | |
| CENP-B_N | 1 | |
| ATP-grasp_2 | 1 | |
| CPL | 1 | |
| Peptidase_M17 | 1 | |
| TRAUB | 1 | |
| Transketolase_N | 1 | |
| Transketolase_C | 1 | |
| TLD | 1 | |
| DUF4151 | 1 | |
| HMA | 1 | |
| ARID | 1 | |
| DUF4205 | 1 | |
| Abhydrolase_2 | 1 | |
| PUB | 1 | |
| Abhydrolase_5 | 1 | |
| zf-RanBP | 1 | |
| I-set | 1 | |
| fn3 | 1 | |
| Ig_2 | 1 | |
| F-box-like | 1 | |
| Linker_histone | 1 | |
| RS4NT | 1 | |
| S4 | 1 | |
| ATP-synt_DE_N | 1 | |
| PH | 1 | |
| Hydrolase_like | 1 | |
| Hydrolase_6 | 1 | |
| PCNA_C | 1 | |
| PCNA_N | 1 | |
| Peptidase_S8 | 1 | |
| NAD_binding_10 | 1 | |
| SRP_SPB | 1 | |
| SRP54_N | 1 | |
| zf-FCS | 1 | |
| RNA_pol_A_bac | 1 | |
| Rieske | 1 | |
| KH_1 | 1 | |
| UDG | 1 | |
| PC4 | 1 | |
| NUC153 | 1 | |
| BRO1 | 1 | |
| ALIX_LYPXL_bnd | 1 | |
| BAF | 1 | |
| Med1 | 1 | |
| PRK | 1 | |
| CLTH | 1 | |
| zf-RING_LisH | 1 | |
| dsrm | 1 | |
| Ribosomal_L2_C | 1 | |
| Ribosomal_L2 | 1 | |
| PP28 | 1 | |
| DUF836 | 1 | |
| Ribosomal_S3_C | 1 | |
| KH_2 | 1 | |
| Hist_deacetyl | 1 | |
| COX5A | 1 | |
| BAH | 1 | |
| NOGCT | 1 | |
| Hat1_N | 1 | |
| AdoHcyase | 1 | |
| Malic_M | 1 | |
| malic | 1 | |
| MitoNEET_N | 1 | |
| Cpn10 | 1 | |
| Sod_Fe_C | 1 | |
| Sod_Fe_N | 1 | |
| DOT1 | 1 | |
| Arrestin_N | 1 | |
| Arrestin_C | 1 | |
| Anticodon_1 | 1 | |
| Acetyltransf_7 | 1 | |
| DEK_C | 1 | |
| DUF1897 | 1 | |
| Enolase_C | 1 | |
| Enolase_N | 1 | |
| DUF543 | 1 | |
| RFX_DNA_binding | 1 | |
| Ribosomal_S7 | 1 | |
| Slu7 | 1 | |
| DUF814 | 1 | |
| Ribosomal_L6 | 1 | |
| Filamin | 1 | |
| Death | 1 | |
| LisH | 1 | |
| 2-oxoacid_dh | 1 | |
| Fork_head | 1 | |
| SSB | 1 | |
| DUF1943 | 1 | |
| TAP_C | 1 | |
| NTF2 | 1 | |
| Tap-RNA_bind | 1 | |
| Pyr_redox_dim | 1 | |
| Exo_endo_phos | 1 | |
| 4HBT | 1 | |
| B2-adapt-app_C | 1 | |
| Alpha_adaptinC2 | 1 | |
| NDK | 1 | |
| PX | 1 | |
| Vps5 | 1 | |
| Peptidase_C12 | 1 | |
| Glutaredoxin | 1 | |
| PGM_PMM_II | 1 | |
| PGM_PMM_I | 1 | |
| PGM_PMM_III | 1 | |
| Spt4 | 1 | |
| Rho_GDI | 1 | |
| Spt5_N | 1 | |
| CTD | 1 | |
| tRNA_bind | 1 | |
| Brix | 1 | |
| NUP50 | 1 | |
| Aminotran_4 | 1 | |
| DHFR_1 | 1 | |
| Ribonuc_red_lgN | 1 | |
| ATP-cone | 1 | |
| Ribonuc_red_sm | 1 | |
| Med12-LCEWAV | 1 | |
| Med12 | 1 | |
| DUF1900 | 1 | |
| DUF1899 | 1 | |
| Cofilin_ADF | 1 | |
| SMC_hinge | 1 | |
| Shugoshin_N | 1 | |
| zf-CHCC | 1 | |
| zf-LYAR | 1 | |
| Myb_DNA-bind_5 | 1 | |
| ProRS-C_1 | 1 | |
| polyprenyl_synt | 1 | |
| Ribosomal_S27 | 1 | |
| Rep-A_N | 1 | |
| Nucleoporin_C | 1 | |
| Nucleoporin_N | 1 |