Lysine acetylation targets protein complexes and co-regulates major cellular functions


Experiment Name
Lysine acetylation targets protein complexes and co-regulates major cellular functions
Citation
Choudhary C,Kumar C,Gnad F,Nielsen ML,Rehman M,Walther TC,Olsen JV,Mann M. Science (New York, N.Y.). 2009-August. Vol 325. 834-40. [pubmed]
Description
MS discovery of acetylation in MV4-11 (myeloid leukemia cell line) cells. Acetyl-lysine antibody pull down plus isoelectric focusing. Addition of KDAC inhibitors SAHA and MS-275 experiment also included
Conditions
Cell
MV4-11
Drug
SAHA
Drug
MS-275
Drug
KDAC Inhibitor
Date Loaded
March 14 2013

Experiment Data Summary

Proteins
890
Measured Peptides
1696
Modification Sites
1749
Rejected Peptides
161
By Residue By Modification Type By Species
K 1749
Acetylation 1749
drosophila melanogaster 1749

Peptide Sequence Profile