Importin-8

Site	Peptide	Modification	Experiment
I6	MDLNRiIQALKGT	None	All human mutations dbSNP All mutations
T13	IIQALKGtIDPKLRI	Phosphothreonine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite Plus Datasets Combined December 3, 2012 Phosphosite Plus Datasets Combined July 3, 2013 PhosphositePlus November 2016 PhosphoSitePlus Datasets Combined June 2016
Y30	ENELNQSyKIINFAP	Phosphotyrosine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 PhosphoSite Plus Datasets, January 9, 2015 PhosphoSite, May 2007 Phosphosite Plus Datasets Combined December 3, 2012 Phosphosite Plus Datasets Combined July 3, 2013 PhosphositePlus November 2016 PhosphoSite Plus Datasets Combined July 11, 2014 PhosphoSitePlus Datasets Combined June 2016
K31	NELNQSYkIINFAPS	Ubiquitination	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite Plus Datasets Combined December 3, 2012 Phosphosite Plus Datasets Combined July 3, 2013 PhosphositePlus November 2016 PhosphoSite Plus Datasets Combined July 11, 2014 dbPTM 3.0 experimentally verified PTM sites
S103	IVEGIIRsPDLVRVQ	Phosphoserine	System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation
K202	YYSVLLQkQILKIFY	Ubiquitination	PhosphositePlus November 2016
Y374	ELWQEDPyEYIRMKF	Phosphotyrosine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite Plus Datasets Combined December 3, 2012 Phosphosite Plus Datasets Combined July 3, 2013 PhosphositePlus November 2016 PhosphoSitePlus Datasets Combined June 2016
S389	DIFEDYAsPTTAAQT	Phosphoserine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite Plus Datasets Combined December 3, 2012 Phosphosite Plus Datasets Combined July 3, 2013 PhosphositePlus November 2016 PhosphoSite Plus Datasets Combined July 11, 2014 dbPTM 3.0 experimentally verified PTM sites Phosphosite, September 2009 March 24 Phosphosite, September 2009 B Phosphosite, September 2009 UniProtKB - MOD_RES HPRD: Human Protein Reference Database Curated Modifications PhosphoSitePlus Datasets Combined June 2016
K510	KKSLIEDkEMPVKVE	Ubiquitination	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite Plus Datasets Combined December 3, 2012 Phosphosite Plus Datasets Combined July 3, 2013 A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles PhosphoSite Plus Datasets Combined July 11, 2014 PhosphositePlus November 2016 dbPTM 3.0 experimentally verified PTM sites
S524	EAALALQsLISNQIQ	Phosphoserine	PhosphositePlus November 2016 PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets, January 9, 2015 PhosphoSitePlus Datasets Combined June 2016
S527	LALQSLIsNQIQAKE	Phosphoserine	PhosphositePlus November 2016 PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets, January 9, 2015 PhosphoSitePlus Datasets Combined June 2016
K565	DVTNVIQkMICEYSQ	N6-acetyllysine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite Plus Datasets Combined December 3, 2012 Phosphosite Plus Datasets Combined July 3, 2013 PhosphositePlus November 2016 acK test
S595	IFGKVLQsDEYEEVE	Phosphoserine	PhosphositePlus November 2016 PhosphoSitePlus Datasets Combined June 2016
Y598	KVLQSDEyEEVEDKT	Phosphotyrosine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 PhosphoSite Plus Datasets, January 9, 2015 PhosphoSite, May 2007 Phosphosite Plus Datasets Combined December 3, 2012 Phosphosite Plus Datasets Combined July 3, 2013 PhosphositePlus November 2016 PhosphoSite Plus Datasets Combined July 11, 2014 Ultra-deep tyrosine phosphoproteomics enabled by a phosphotyrosine superbinder Tyrosine Phosphorylation of the Lyn Src Homology 2 (SH2) Domain Modulates Its Binding Affinity and Specificity Phosphosite, September 2009 March 24 Phosphosite, September 2009 B Phosphosite, September 2009 PhosphoSitePlus Datasets Combined June 2016
I640	ENICLRIiDLVLQKH	None	All human mutations dbSNP All mutations
S902	MEENEEIsSDEEETN	Phosphoserine	PhosphoSite Plus Datasets, January 9, 2015 UniProtKB - MOD_RES PhosphoSite Plus Datasets Combined July 11, 2014 Phosphosite, September 2009 UniProtKB - MOD_RES System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation UniprotKB - MOD_RES Proteogenomics connects somatic mutations to signalling in breast cancer PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined December 3, 2012 Phosphosite Plus Datasets Combined July 3, 2013 dbPTM 3.0 experimentally verified PTM sites Phosphosite, September 2009 March 24 UniprotKB MOD_RES Dec. 16, 2016 UniProtKB - MOD_RES Phospho.ELM v9.0 Phosphosite, September 2009 B HPRD: Human Protein Reference Database Curated Modifications PhosphositePlus November 2016 UniProtKB - MOD_RES UniProtKB - MOD_RES UniProtKB - MOD_RES UniProtKB KMN PhosphoSitePlus Datasets Combined June 2016
S903	EENEEISsDEEETNV	Phosphoserine	PhosphoSite Plus Datasets, January 9, 2015 UniProtKB - MOD_RES PhosphoSite Plus Datasets Combined July 11, 2014 Phosphosite, September 2009 UniProtKB - MOD_RES System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation UniprotKB - MOD_RES PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 Phosphosite Plus Datasets Combined December 3, 2012 Phosphosite Plus Datasets Combined July 3, 2013 dbPTM 3.0 experimentally verified PTM sites Phosphosite, September 2009 March 24 UniprotKB MOD_RES Dec. 16, 2016 UniProtKB - MOD_RES Phospho.ELM v9.0 Phosphosite, September 2009 B HPRD: Human Protein Reference Database Curated Modifications PhosphositePlus November 2016 UniProtKB - MOD_RES UniProtKB - MOD_RES UniProtKB - MOD_RES UniProtKB KMN PhosphoSitePlus Datasets Combined June 2016
T908	ISSDEEEtNVTAQAM	Phosphothreonine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite Plus Datasets Combined December 3, 2012 Phosphosite Plus Datasets Combined July 3, 2013 PhosphositePlus November 2016 PhosphoSite Plus Datasets Combined July 11, 2014 dbPTM 3.0 experimentally verified PTM sites Phosphosite, September 2009 March 24 Phosphosite, September 2009 B Phosphosite, September 2009 PhosphoSitePlus Datasets Combined June 2016 HPRD: Human Protein Reference Database Curated Modifications Proteogenomics connects somatic mutations to signalling in breast cancer
Y995	RTALQEVyTLAEHRR	Phosphotyrosine	Ultra-deep tyrosine phosphoproteomics enabled by a phosphotyrosine superbinder
T1003	TLAEHRRtVAEAKKK	Phosphothreonine	PhosphoSitePlus Datasets Combined June 15, 2015 PhosphoSite Plus Datasets Combined January 10, 2014 PhosphoSite Plus Datasets, January 9, 2015 Phosphosite Plus Datasets Combined December 3, 2012 Phosphosite Plus Datasets Combined July 3, 2013 PhosphositePlus November 2016 PhosphoSite Plus Datasets Combined July 11, 2014 dbPTM 3.0 experimentally verified PTM sites System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation PhosphoSitePlus Datasets Combined June 2016