Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML


Experiment Name
Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML
Citation
Winter GE,Rix U,Carlson SM,Gleixner KV,Grebien F,Gridling M,Muller AC,Breitwieser FP,Bilban M,Colinge J,Valent P,Bennett KL,White FM,Superti-Furga G. Nature chemical biology. 2012-October. Vol 8. 905-12. [pubmed]
Description
Quantitative measurement of phosphorylation in a BCR-ABLT315I mouse model. Treatment includes control and addition of tyrosine kinase inhibitors (bosutinib, danusertib, and the combination)
Conditions
Drug
danusertib
Drug
bosutinib
Cell
Ba/F3 BCR-ABLT315I
Date Loaded
May 23 2016

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