Global Survey of Phosphotyrosine Signaling Identifies Oncogenic Kinases in Lung Cancer
PFAM Sites
| Site | Peptides | |
|---|---|---|
| None | 574 | |
| Pkinase_Tyr | 59 | |
| Pkinase | 22 | |
| SH2 | 12 | |
| His_Phos_1 | 7 | |
| S_100 | 4 | |
| C2 | 3 | |
| Proteasome | 3 | |
| GTP_EFTU | 3 | |
| G6PD_C | 3 | |
| CH | 3 | |
| Globin | 3 | |
| Myosin_head | 3 | |
| ERp29_N | 2 | |
| Serum_albumin | 2 | |
| PBD | 2 | |
| EF_hand_5 | 2 | |
| PH | 2 | |
| Ldh_1_C | 2 | |
| Ig_2 | 2 | |
| fn3 | 2 | |
| Catalase | 2 | |
| Aminotran_1_2 | 2 | |
| Sec23_helical | 2 | |
| Enolase_N | 2 | |
| Filamin | 2 | |
| G-alpha | 2 | |
| Ras | 2 | |
| Integrin_b_cyt | 2 | |
| Amidase | 2 | |
| Transferrin | 2 | |
| LST1 | 2 | |
| PX | 2 | |
| Histone | 2 | |
| Glycolytic | 1 | |
| Transketolase_N | 1 | |
| ACBP | 1 | |
| PG_binding_1 | 1 | |
| S10_plectin | 1 | |
| GARS_C | 1 | |
| NDK | 1 | |
| Alpha_adaptinC2 | 1 | |
| EF_hand_4 | 1 | |
| KH_1 | 1 | |
| Ank_4 | 1 | |
| Enolase_C | 1 | |
| Cpn10 | 1 | |
| MGS | 1 | |
| tRNA-synt_1c | 1 | |
| SP_C-Propep | 1 | |
| LMWPc | 1 | |
| ATP-gua_Ptrans | 1 | |
| tRNA_SAD | 1 | |
| WH1 | 1 | |
| RA | 1 | |
| BAH | 1 | |
| FumaraseC_C | 1 | |
| B2-adapt-app_C | 1 | |
| DEAD | 1 |
PFAM Domains
| Domain | Peptides | |
|---|---|---|
| None | 128 | |
| Pkinase_Tyr | 33 | |
| SH2 | 27 | |
| Pkinase | 27 | |
| SH3_1 | 23 | |
| CH | 14 | |
| PH | 12 | |
| PDZ | 10 | |
| C2 | 9 | |
| Ig_2 | 8 | |
| fn3 | 7 | |
| FERM_M | 6 | |
| RRM_1 | 6 | |
| LIM | 6 | |
| SAM_1 | 5 | |
| RhoGAP | 5 | |
| EF_hand_5 | 5 | |
| IRS | 5 | |
| V-set | 5 | |
| SH3_2 | 5 | |
| Y_phosphatase | 5 | |
| I-set | 4 | |
| Serine_rich | 3 | |
| Ephrin_lbd | 3 | |
| WH1 | 3 | |
| Bromodomain | 3 | |
| Exo_endo_phos | 3 | |
| RRM_6 | 3 | |
| FERM_N | 3 | |
| Filamin | 3 | |
| STAT_bind | 3 | |
| STAT_int | 3 | |
| C1_1 | 3 | |
| Globin | 3 | |
| Spectrin | 3 | |
| efhand_Ca_insen | 3 | |
| Ank_4 | 3 | |
| RA | 3 | |
| zf-H2C2_2 | 3 | |
| Focal_AT | 2 | |
| GTPase_binding | 2 | |
| Proteasome | 2 | |
| Proteasome_A_N | 2 | |
| PBD | 2 | |
| PCAF_N | 2 | |
| Acetyltransf_7 | 2 | |
| Talin_middle | 2 | |
| VBS | 2 | |
| Ldh_1_C | 2 | |
| S10_plectin | 2 | |
| Fibrinogen_C | 2 | |
| Ig_3 | 2 | |
| TIG | 2 | |
| Aminotran_1_2 | 2 | |
| RhoGEF | 2 | |
| APP_E2 | 2 | |
| APP_N | 2 | |
| APP_Cu_bd | 2 | |
| Kunitz_BPTI | 2 | |
| tRNA-synt_2b | 2 | |
| DEAD | 2 | |
| Recep_L_domain | 2 | |
| Profilin | 2 | |
| adh_short_C2 | 2 | |
| PDZ_assoc | 2 | |
| VWA | 2 | |
| S_100 | 2 | |
| Cofilin_ADF | 2 | |
| F5_F8_type_C | 2 | |
| Sushi | 2 | |
| G-alpha | 2 | |
| Integrin_B_tail | 2 | |
| zf-C3HC4_3 | 2 | |
| Myosin_head | 2 | |
| Myosin_N | 2 | |
| SAM_2 | 2 | |
| Glycolytic | 1 | |
| ERp29_N | 1 | |
| ERp29 | 1 | |
| Serum_albumin | 1 | |
| efhand_like | 1 | |
| Acyl-CoA_dh_M | 1 | |
| CAP_GLY | 1 | |
| MAM | 1 | |
| Transketolase_N | 1 | |
| Transket_pyr | 1 | |
| Transketolase_C | 1 | |
| GTP_EFTU | 1 | |
| GTP_EFTU_D3 | 1 | |
| GTP_EFTU_D2 | 1 | |
| G6PD_C | 1 | |
| G6PD_N | 1 | |
| Thioredoxin_8 | 1 | |
| ACBP | 1 | |
| Peptidase_M10 | 1 | |
| PG_binding_1 | 1 | |
| GARS_A | 1 | |
| Formyl_trans_N | 1 | |
| GARS_N | 1 | |
| AIRS_C | 1 | |
| GARS_C | 1 | |
| AIRS | 1 | |
| ig | 1 | |
| Catalase | 1 | |
| adh_short | 1 | |
| LSR | 1 | |
| NDK | 1 | |
| DnaJ | 1 | |
| DnaJ_C | 1 | |
| DnaJ_CXXCXGXG | 1 | |
| B2-adapt-app_C | 1 | |
| Alpha_adaptinC2 | 1 | |
| EF_hand_4 | 1 | |
| FAD_binding_7 | 1 | |
| DNA_photolyase | 1 | |
| 4_1_CTD | 1 | |
| SAB | 1 | |
| FERM_C | 1 | |
| F_actin_bind | 1 | |
| DUF3481 | 1 | |
| CG-1 | 1 | |
| Transglut_N | 1 | |
| Transglut_C | 1 | |
| PET | 1 | |
| CRAL_TRIO_2 | 1 | |
| NUC194 | 1 | |
| Metallophos | 1 | |
| FerB | 1 | |
| FerI | 1 | |
| FerA | 1 | |
| Sec23_trunk | 1 | |
| Sec23_helical | 1 | |
| Sec23_BS | 1 | |
| zf-Sec23_Sec24 | 1 | |
| Gelsolin | 1 | |
| PUB | 1 | |
| UBX | 1 | |
| GIDA_assoc_3 | 1 | |
| KH_1 | 1 | |
| Clathrin_H_link | 1 | |
| Clathrin-link | 1 | |
| VGCC_beta4Aa_N | 1 | |
| WW | 1 | |
| NO_synthase | 1 | |
| FAD_binding_1 | 1 | |
| Flavodoxin_1 | 1 | |
| NAD_binding_1 | 1 | |
| DUF1900 | 1 | |
| DUF1899 | 1 | |
| IBN_N | 1 | |
| His_Phos_1 | 1 | |
| OMPdecase | 1 | |
| Pribosyltran | 1 | |
| Ank_2 | 1 | |
| Ank_5 | 1 | |
| zf-DHHC | 1 | |
| Anticodon_1 | 1 | |
| GST_N | 1 | |
| GST_C | 1 | |
| Hydrolase | 1 | |
| Cation_ATPase_N | 1 | |
| Enolase_C | 1 | |
| Enolase_N | 1 | |
| DUF1866 | 1 | |
| ABC_tran | 1 | |
| MAGUK_N_PEST | 1 | |
| L27_1 | 1 | |
| Adenylsucc_synt | 1 | |
| Anth_Ig | 1 | |
| Death | 1 | |
| efhand | 1 | |
| Pescadillo_N | 1 | |
| Cpn10 | 1 | |
| DEP | 1 | |
| Thiolase_C | 1 | |
| Thiolase_N | 1 | |
| EGF_CA | 1 | |
| cEGF | 1 | |
| Lectin_C | 1 | |
| Pyr_redox_2 | 1 | |
| Pyr_redox_dim | 1 | |
| Glutaredoxin | 1 | |
| MGS | 1 | |
| tRNA-synt_1c | 1 | |
| tRNA-synt_1c_C | 1 | |
| ubiquitin | 1 | |
| UEV | 1 | |
| Vps23_core | 1 | |
| Receptor_2B4 | 1 | |
| MVP_shoulder | 1 | |
| HATPase_c_3 | 1 | |
| BTB | 1 | |
| PseudoU_synth_1 | 1 | |
| Band_3_cyto | 1 | |
| HATPase_c | 1 | |
| K_tetra | 1 | |
| Ras | 1 | |
| Integrin_b_cyt | 1 | |
| Amidase | 1 | |
| SP_C-Propep | 1 | |
| BRICHOS | 1 | |
| Cu-oxidase_2 | 1 | |
| Cu-oxidase | 1 | |
| Cu-oxidase_3 | 1 | |
| LMWPc | 1 | |
| ATP-gua_Ptrans | 1 | |
| ATP-gua_PtransN | 1 | |
| COG4 | 1 | |
| Cbl_N | 1 | |
| Cbl_N3 | 1 | |
| Cbl_N2 | 1 | |
| Transferrin | 1 | |
| Reprolysin | 1 | |
| Disintegrin | 1 | |
| HGTP_anticodon | 1 | |
| tRNA_SAD | 1 | |
| VASP_tetra | 1 | |
| Fib_alpha | 1 | |
| Fibrinogen_aC | 1 | |
| Methyltransf_31 | 1 | |
| PID | 1 | |
| DNA_methylase | 1 | |
| DNMT1-RFD | 1 | |
| BAH | 1 | |
| DMAP_binding | 1 | |
| zf-CXXC | 1 | |
| RRM_5 | 1 | |
| Hrs_helical | 1 | |
| Calx-beta | 1 | |
| Lyase_1 | 1 | |
| FumaraseC_C | 1 | |
| BPS | 1 | |
| LST1 | 1 | |
| PI3K_p85B | 1 | |
| PI3K_rbd | 1 | |
| Bcr-Abl_Oligo | 1 | |
| Connexin_CCC | 1 | |
| PX | 1 | |
| Homeobox | 1 | |
| WAC_Acf1_DNA_bd | 1 | |
| PHD | 1 | |
| Peptidase_M14 | 1 | |
| CarboxypepD_reg | 1 | |
| Defensin_1 | 1 | |
| Histone | 1 |