ProteomeScout Summary Statistics

All Data

Registered Users 115
Experiments 33
Compendia 7
Datasets 78
Species 2930
Proteins 92943
Measured Peptides 1213752
Modified Residues 750962
Modified Sites 723113
PTM Types 209

Modified Sites

Modifications by Residue (Top 5)
Modifications by Source
W1siUyIsIDY0OTcxOF0sIFsiSyIsIDIxNTQ2MF0sIFsiVCIsIDE4MTc5NF0sIFsiWSIsIDExNTkyOF0sIFsiTiIsIDQwODkzXSwgWyJPdGhlciIsIDQ1NzE0XV0=
W1siUGhvc3Bob3NpdGVQbHVzIE5vdmVtYmVyIDIwMTYiLCA0NzcyNjVdLCBbIlBob3NwaG8uRUxNIHY5LjAiLCAzNjM3MV0sIFsiTy1HbHljQmFzZSB2Ni4wMCIsIDgwN10sIFsiZGJQVE0gMy4wIGV4cGVyaW1lbnRhbGx5IHZlcmlmaWVkIFBUTSBzaXRlcyIsIDIxNjk5MV0sIFsiSFBSRDogSHVtYW4gUHJvdGVpbiBSZWZlcmVuY2UgRGF0YWJhc2UgQ3VyYXRlZCBNb2RpZmljYXRpb25zIiwgNjUzMjBdLCBbImV4cGVyaW1lbnQiLCAyMjg2ODhdLCBbIlVuaXByb3RLQiBNT0RfUkVTIERlYy4gMTYsIDIwMTYiLCAxOTk1OTBdLCBbIlVuaVByb3RLQiBDQVJCT0hZRCIsIDI0NDc1XV0=
Modifications by Type (Top 5)
Modifications by Species (Top 5)
W1siUGhvc3Bob3NlcmluZSIsIDY0MzMxNF0sIFsiUGhvc3Bob3RocmVvbmluZSIsIDE3NzQ2NF0sIFsiUGhvc3Bob3R5cm9zaW5lIiwgMTEzNDI4XSwgWyJVYmlxdWl0aW5hdGlvbiIsIDEwNTQ1Nl0sIFsiTjYtYWNldHlsbHlzaW5lIiwgNzcwNThdLCBbIk90aGVyIiwgMTMyNzg3XV0=
W1siaG9tbyBzYXBpZW5zIiwgNzczNTExXSwgWyJtdXMgbXVzY3VsdXMiLCAyNTEyNDRdLCBbInJhdHR1cyBub3J2ZWdpY3VzIiwgNzU0MTJdLCBbIlNhY2NoYXJvbXljZXMgY2VyZXZpc2lhZSIsIDIyODk5XSwgWyJib3MgdGF1cnVzIiwgMTcwOTldLCBbIk90aGVyIiwgMTA5MzQyXV0=
Modifications Reported among Compendia
eyJvdmVybGFwcyI6IFt7InNpemUiOiA0MTg4OCwgInNldHMiOiBbMCwgMV19LCB7InNpemUiOiAyMDkzNCwgInNldHMiOiBbMCwgMl19LCB7InNpemUiOiA3NTE3NCwgInNldHMiOiBbMSwgMl19LCB7InNpemUiOiAyMDM3OSwgInNldHMiOiBbMCwgMSwgMl19XSwgInNldHMiOiBbeyJzaXplIjogNjUzMjAsICJsYWJlbCI6ICJIUFJEOiBIdW1hbiBQcm90ZWluIFJlZmVyZW5jZSBEYXRhYmFzZSBDdXJhdGVkIE1vZGlmaWNhdGlvbnMifSwgeyJzaXplIjogNDc3MjY1LCAibGFiZWwiOiAiUGhvc3Bob3NpdGVQbHVzIE5vdmVtYmVyIDIwMTYifSwgeyJzaXplIjogMTk5NTkwLCAibGFiZWwiOiAiVW5pcHJvdEtCIE1PRF9SRVMgRGVjLiAxNiwgMjAxNiJ9XX0=
Novel Modifications Reported in Experiments
eyJvdmVybGFwcyI6IFt7InNpemUiOiA3NjMzMCwgInNldHMiOiBbMCwgMV19XSwgInNldHMiOiBbeyJzaXplIjogNjg3NDQ5LCAibGFiZWwiOiAiY29tcGVuZGlhIn0sIHsic2l6ZSI6IDEzOTg0MywgImxhYmVsIjogImV4cGVyaW1lbnRzIn1dfQ==

Modified Sites By Grouping

By Residue By Modification Type (Top 50) By Species (Top 50)
A 4980
C 6486
D 302
E 1350
F 837
G 1193
H 384
I 135
K 215460
L 529
M 3974
N 40893
P 2711
Q 1479
R 20691
S 649718
T 181794
V 438
W 225
Y 115928
Phosphoserine 643314
Phosphothreonine 177464
Phosphotyrosine 113428
Ubiquitination 105456
N6-acetyllysine 77058
N-Glycosylation 40266
Methylation 15790
N6-(pyridoxal phosphate)lysine 8168
Sumoylation 8045
N6-succinyllysine 5748
O-Glycosylation 5672
N-acetylalanine 4862
Omega-N-methylarginine 3680
N-acetylmethionine 3675
S-nitrosocysteine 3423
Dimethylation 2687
N-acetylserine 2566
N6-methyllysine 1847
Asymmetric dimethylarginine 1641
3-oxoalanine (Cys) 1413
Pyrrolidone carboxylic acid 1341
Hydroxylation 1252
N6,N6-dimethyllysine 1207
4-carboxyglutamate 1084
4-hydroxyproline 917
2',4',5'-topaquinone 917
Sulfotyrosine 913
Phenylalanine amide 816
Cysteine methyl ester 684
N6,N6,N6-trimethyllysine 647
Acetylation 619
Pyruvic acid (Ser) 579
N6-carboxylysine 533
N6-crotonyl-L-lysine 525
N-acetylthreonine 505
Leucine amide 503
O-(pantetheine 4'-phosphoryl)serine 484
N6-lipoyllysine 458
1-thioglycine 438
Citrulline 430
Palmitoylation 411
Nitrated tyrosine 380
5-hydroxylysine 374
Valine amide 336
Trimethylation 320
Hydroxyproline 298
Symmetric dimethylarginine 281
Omega-N-methylated arginine 224
N-acetylglycine 222
N-myristoyl glycine 204
homo sapiens 773511
mus musculus 251244
rattus norvegicus 75412
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 22899
bos taurus 17099
drosophila melanogaster 11218
Schizosaccharomyces pombe (strain 972 / ATCC 24843) 7333
Pongo abelii 7222
arabidopsis thaliana 6707
Candida albicans (strain SC5314 / ATCC MYA-2876) 5326
sus scrofa 4925
caenorhabditis elegans 3803
oryctolagus cuniculus 3345
Canis lupus familiaris 2377
gallus gallus 2292
Pan troglodytes 1935
ovis aries 1162
equus caballus 981
Macaca mulatta 930
mycoplasma pneumoniae (strain ATCC 29342 / M129) 880
danio rerio 694
Felis catus 685
cavia porcellus 667
Gorilla gorilla gorilla 649
callithrix jacchus 579
Saccharomyces cerevisiae (strain YJM789) 564
Human cytomegalovirus (strain AD169) 488
dictyostelium discoideum 390
Human cytomegalovirus (strain Merlin) 358
Oryza sativa subsp. japonica 356
Escherichia coli (strain K12) 350
candida albicans 333
Takifugu rubripes 303
Xenopus tropicalis 292
Mytilus edulis 273
xenopus laevis 269
Acanthamoeba polyphaga mimivirus 265
Ailuropoda melanoleuca 247
Papio anubis 228
Mustela putorius furo 224
Otolemur garnettii 209
Loxodonta africana 207
Human herpesvirus 6A (strain Uganda-1102) 202
Saccharomyces cerevisiae (strain RM11-1a) 202
Aplysia californica 199
Oryza sativa subsp. indica 197
zea mays 194
Solanum tuberosum 190
Solanum lycopersicum 184
Ictidomys tridecemlineatus 180

Supported PTM Types: 366

Name Aliases Residues Species Position Monoisotopic Mass Average Mass
Blocked amino end (Pro) P archaea, bacteria, eukaryota n-terminal
N6-poly(methylaminopropyl)lysine METH, POLYM K cylindrotheca fusiformis anywhere 426.441 426.73
S-Nitrosylation NTRY C mammalia, proteobacteria 28.9902 28.9982
+ S-nitrosocysteine NTRY, s-nitrosylation C mammalia, proteobacteria anywhere 28.9902 29.0
Lysine derivative K archaea, bacteria, eukaryota
N-[(12R)-12-hydroxymyristoyl]cysteine myristate C n-terminal 226.193 226.36
1-thioglycine THIOG G bacteria, eukaryota, euryarchaeota core 15.9772 16.07
Methionine sulfone MSONE, oxidation M proteus mirabilis anywhere 31.9898 32.0
Phosphorylation PHOS C, D, H, R, S, T, Y archaea, bacteria, cryptophyta, eukaryota, euryarchaeota, fungi, mammalia, proteobacteria, rhodophyta, sulfolobus solfataricus, viridiplantae 79.9663 79.9799
+ 4-aspartylphosphate PHOS, phosphoprotein, phosphorylation D bacteria, cryptophyta, euryarchaeota, fungi, rhodophyta, viridiplantae anywhere 79.9663 79.98
+ Phosphocysteine PHOS, phosphoprotein, phosphorylation C bacteria anywhere 79.9663 79.98
+ Phosphoarginine PHOS, phosphoprotein, phosphorylation R mammalia anywhere 79.9663 79.98
+ Phosphohistidine PHOS, phosphoprotein, phosphorylation H archaea, bacteria, eukaryota anywhere 79.9663 79.98
+ Phosphoserine PHOS, phosphoprotein, phosphorylation S archaea, bacteria, eukaryota anywhere 79.9663 79.98
+ Phosphothreonine PHOS, phosphoprotein, phosphorylation T bacteria, eukaryota anywhere 79.9663 79.98
+ Phosphotyrosine PHOS, phosphoprotein, phosphorylation Y eukaryota, proteobacteria, sulfolobus solfataricus anywhere 79.9663 79.98
+ Pros-phosphohistidine PHOS, phosphoprotein, phosphorylation H bacteria anywhere 79.9663 79.98
+ Tele-phosphohistidine PHOS, phosphoprotein, phosphorylation H bacteria anywhere 79.9663 79.98
3-oxoalanine (Cys) OXOAC C chlorophyta, firmicutes, metazoa, proteobacteria anywhere -17.9928 -18.08
Cholesterol CHOL G metazoa 368.344 368.64
+ Cholesterol glycine ester CHOL, cholesterol, lipoprotein G metazoa c-terminal 368.344 368.64
N6-(3,6-diaminohexanoyl)-5-hydroxylysine HYDR, hydroxylation K bacteria anywhere
Thyroxine THRX, iodination Y mammalia anywhere 595.613 595.68
N,N-dimethylleucine METH L petrosia ficiformis n-terminal 28.0313 28.06
Blocked amino end (Thr) T archaea, bacteria, eukaryota n-terminal
GPI-like-anchor amidated asparagine gpi-anchor N c-terminal
Aspartyl isopeptide (Asp) D momordica cochinchinensis core
5-glutamyl N2-lysine isopeptide bond E archaea, deinococcus-thermus c-terminal 128.095 128.17
Tryptophylquinone W proteobacteria anywhere 29.9742 29.98
(4R)-4,5-dihydroxyleucine HYDR, hydroxylation L amanita virosa anywhere 31.9898 32.0
4,5,5'-trihydroxyleucine HYDR, hydroxylation L amanita virosa anywhere 47.9847 48.0
(3R,4R)-4,5-dihydroxyisoleucine HYDR, hydroxylation I amanita phalloides anywhere 31.9898 32.0
(3R)-3-hydroxyaspartate HYDR, hydroxylation D mammalia, streptoverticillium griseoverticillatum anywhere 15.9949 16.0
(E)-2,3-didehydrotyrosine Y cnidaria core -2.01565 -2.02
N6-(retinylidene)lysine retinal protein K euryarchaeota, gammaproteobacteria anywhere 266.203 266.42
5-glutamyl polyglycine E eukaryota anywhere
Beta-decarboxylated aspartate D homo sapiens anywhere -43.9898 -44.01
GPI-anchor amidated threonine gpi-anchor T mus musculus c-terminal
Blocked amino end (Val) V archaea, bacteria, eukaryota n-terminal
(3S)-3-hydroxyaspartate HYDR, hydroxylation D metazoa anywhere 15.9949 16.0
Aspartic acid 1-[(3-aminopropyl)(5'-adenosyl)phosphono]amide phosphoprotein N escherichia coli c-terminal 386.11 386.3
N6-malonyllysine K archaea, bacteria, eukaryota anywhere 214.095 214.22
D-threonine d-amino acid T amanita virosa core
(3R)-3-hydroxyasparagine HYDR, hydroxylation N mammalia anywhere 15.9949 16.0
Blocked amino end (Ser) S archaea, bacteria, eukaryota n-terminal
Nitrated tyrosine nitration Y eukaryota anywhere 44.9851 45.0
Cyclo[(prolylserin)-O-yl] cysteinate C actinobacteria c-terminal
3-hydroxyphenylalanine HYDR, hydroxylation F planobispora rosea anywhere 15.9949 16.0
Omega-hydroxyceramide glutamate ester OHC, lipoprotein Q homo sapiens anywhere 760.731 761.29
(Z)-2,3-didehydrotyrosine DHY Y cnidaria core -2.01565 -2.02
Cysteine derivative C archaea, bacteria, eukaryota
D-asparagine d-amino acid N achatina fulica core
O-(2-aminoethylphosphoryl)serine phosphoprotein S neisseriales anywhere 123.009 123.05
Cysteine sulfenic acid (-SOH) CSEA, oxidation C bacteria, euryarchaeota, mammalia anywhere 15.9949 16.0
Dimethylation of proline DIMETP 29.0391 29.06
Palmitoylation PALM C, K, S, T bacteria, chordata, eukaryota, metazoa, proteobacteria, vertebrata, viruses 238.23 238.414
+ S-palmitoyl cysteine PALM, palmitate, palmitoylation C eukaryota anywhere 238.23 238.41
+ N-palmitoyl cysteine PALM, palmitate, palmitoylation C bacteria, metazoa n-terminal 238.23 238.41
+ N6-palmitoyl lysine PALM, palmitate, palmitoylation K proteobacteria, vertebrata anywhere 238.23 238.41
+ O-palmitoyl serine PALM, palmitate, palmitoylation S chordata, viruses anywhere 238.23 238.41
+ O-palmitoyl threonine PALM, palmitate, palmitoylation T chordata anywhere 238.23 238.41
n-Octanoate OCTA S, T lithobates catesbeiana, vertebrata 126.104 126.199
+ O-octanoyl serine OCTA, lipoprotein, n-octanoate S vertebrata anywhere 126.104 126.2
+ O-octanoyl threonine OCTA, lipoprotein, n-octanoate T lithobates catesbeiana anywhere 126.104 126.2
GPI-like-anchor amidated serine gpi-anchor S dictyostelium discoideum c-terminal
Arginine derivative R archaea, bacteria, eukaryota
N-D-glucuronoyl glycine glycoprotein G n-terminal 176.032 176.12
6'-chlorotryptophan W anywhere 33.961 34.45
Pyrrolidone carboxylic acid (Glu) PYRE, PYRR, pyrrolidone carboxylic acid E bos taurus n-terminal -18.0106 -18.02
N6-succinyllysine K archaea, bacteria, eukaryota anywhere 100.016 100.07
D-serine (Cys) d-amino acid C amanita virosa core -15.9772 -16.07
GPI-anchor amidated alanine gpi-anchor A eukaryota c-terminal
Blocked amino end (Gly) G archaea, bacteria, eukaryota n-terminal
D-methionine d-amino acid M phyllomedusa sauvagei core
O-(5'-phospho-DNA)-tyrosine covalent protein-dna linkage, phosphoprotein Y viruses anywhere
(3S)-3-hydroxyasparagine HYDR, hydroxylation N vertebrata anywhere 15.9949 16.0
FAD FAD C, H, Y bacteria, eukaryota, pseudomonas putida 783.141 783.542
+ O-8alpha-FAD tyrosine fad Y pseudomonas putida anywhere 783.141 783.53
+ Pros-8alpha-FAD histidine fad, flavoprotein H bacteria, eukaryota anywhere 783.141 783.53
+ S-8alpha-FAD cysteine fad C bacteria, eukaryota anywhere 783.141 783.53
+ Tele-8alpha-FAD histidine fad H bacteria, eukaryota anywhere 783.141 783.53
Dihydroxylation DIHYDR K, P, R mytilus edulis, styela clava 31.9898 32.0
+ 4,5-dihydroxylysine DIHYDR, HYDR, dihydroxylation, hydroxylation K styela clava anywhere 31.9898 32.0
+ 3,4-dihydroxyarginine DIHYDR, HYDR, dihydroxylation, hydroxylation R styela clava anywhere 31.9898 32.0
+ 3,4-dihydroxyproline DIHYDR, HYDR, dihydroxylation, hydroxylation P mytilus edulis anywhere 31.9898 32.0
D-allo-isoleucine d-amino acid I amphibia core
Pentaglycyl murein peptidoglycan amidated alanine peptidoglycan-anchor A peptostreptococcus magnus anywhere
N6-carboxylysine K bacteria, cryptophyta, euglenozoa, eukaryota, euryarchaeota, rhodophyta, stramenopiles, viridiplantae anywhere 43.9898 44.01
5-glutamyl glycerylphosphorylethanolamine phosphoprotein E eukaryota anywhere 197.045 197.13
n-Decanoate DECA C, S, T bacteria, lithobates catesbeiana 241.168 241.33
+ S-diacylglycerol cysteine DIAC, lipoprotein, s-diacylglycerol cysteine C bacteria n-terminal 576.512 576.93
+ O-decanoyl serine DECA, lipoprotein, n-decanoate S anywhere 154.136 154.25
+ O-decanoyl threonine DECA, lipoprotein, n-decanoate T lithobates catesbeiana anywhere 154.136 154.25
Alanine derivative A archaea, bacteria, eukaryota
Sulfation SULF S, T, Y homo sapiens, metazoa, plasmodium falciparum (isolate 3d7), viridiplantae 79.9568 80.0642
+ Sulfoserine SULF, sulfation S homo sapiens anywhere 79.9568 80.06
+ Sulfothreonine SULF, sulfation T plasmodium falciparum (isolate 3d7) anywhere 79.9568 80.06
+ Sulfotyrosine SULF, sulfation Y metazoa, viridiplantae anywhere 79.9568 80.06
(3S,4R)-3,4-dihydroxyisoleucine HYDR, hydroxylation I streptomyces azureus anywhere 31.9898 32.0
Aminomalonic acid (Ser) S polypedates leucomystax anywhere 13.9793 13.98
S-archaeol ARCH C euryarchaeota 634.663 635.14
+ S-archaeol cysteine ARCH, lipoprotein, s-archaeol C euryarchaeota n-terminal 634.663 635.14
2,3-didehydroalanine (Ser) DHAS S bacteria, eukaryota, euryarchaeota core -18.0106 -18.02
GPI-anchor amidated glycine gpi-anchor G eukaryota c-terminal
Geranyl-geranylation GERA C eukaryota 272.25 272.474
+ S-geranylgeranyl cysteine GERA, geranyl-geranylation, prenylation C eukaryota anywhere 272.25 272.47
Pyruvic acid (Ser) PYRUS, pyruvate S archaea, bacteria, eukaryota n-terminal -17.0265 -17.03
3'-geranyl-2',N2-cyclotryptophan prenylation W bacillus subtilis anywhere 136.125 136.23
(5R)-5-hydroxylysine HYDR, hydroxylation K metazoa anywhere 15.9949 16.0
FMN conjugation (His) FMNH H 454.089 454.33
+ Tele-8alpha-FMN histidine FMNH, fmn, fmn conjugation (his) H anywhere 454.089 454.33
Bromination BROM H, W clypeaster japonicus, metazoa 77.9105 78.9
+ 6'-bromotryptophan BROM, bromination W metazoa anywhere 77.9105 78.9
+ Bromohistidine BROM, bromination H clypeaster japonicus anywhere 77.9105 78.9
Blocked amino end (Met) M archaea, bacteria, eukaryota n-terminal
Methylation METH A, C, E, F, H, I, K, L, M, N, P, Q, R, S, T, Y actinobacteria, archaea, bacteria, chlamydomonas reinhardtii, cryptophyta, cyanobacteria, drosophila melanogaster, eukaryota, euryarchaeota, fungi, leishmania donovani, lysinibacillus sphaericus, mammalia, metazoa, methanothermobacter marburgensis (strain dsm 2133 / 14651 / nbrc 100331 / ocm 82 / marburg), petrosia ficiformis, physarum polycephalum, proteobacteria, pseudomonas putida, rhodophyta, saccharomyces cerevisiae, vertebrata 14.0157 14.0269
+ N-methylserine METH, methylation S eukaryota n-terminal 14.0156 14.03
+ O-methylthreonine METH, methylation T anywhere 14.0156 14.03
+ S-methylcysteine METH, methylation C chlamydomonas reinhardtii, eukaryota, euryarchaeota, lysinibacillus sphaericus anywhere 14.0156 14.03
+ Leucine methyl ester methyl ester L vertebrata c-terminal 14.0156 14.03
+ N6-methyllysine METH, methylation K archaea, bacteria, eukaryota anywhere 14.0156 14.03
+ Omega-N-methylarginine METH, methylation R leishmania donovani, mammalia anywhere 14.0156 14.03
+ Pros-methylhistidine METH, methylation H euryarchaeota, vertebrata anywhere 14.0156 14.03
+ 5-methylarginine METH, methylation R euryarchaeota anywhere 14.0156 14.03
+ N-methylproline METH, methylation P drosophila melanogaster n-terminal 14.0156 14.03
+ N-methylleucine METH, methylation L petrosia ficiformis, proteobacteria n-terminal 14.0156 14.03
+ N5-methylarginine METH, methylation R saccharomyces cerevisiae anywhere 14.0156 14.03
+ 2-methylglutamine METH, methylation Q methanothermobacter marburgensis (strain dsm 2133 / 14651 / nbrc 100331 / ocm 82 / marburg) core 14.0156 14.03
+ Cysteine methyl ester methyl ester C actinobacteria, fungi, metazoa c-terminal 14.0156 14.03
+ Glutamate methyl ester (Glu) methyl ester E bacteria, euryarchaeota anywhere 14.0156 14.03
+ Lysine methyl ester methyl ester K saccharomyces cerevisiae c-terminal 14.0156 14.03
+ Methylhistidine METH, methylation H euryarchaeota, physarum polycephalum, vertebrata anywhere 14.0156 14.03
+ N-methylalanine METH, methylation A eukaryota, proteobacteria n-terminal 14.0156 14.03
+ N-methylisoleucine METH, methylation I pseudomonas putida n-terminal 14.0156 14.03
+ N-methylmethionine METH, methylation M chlamydomonas reinhardtii, proteobacteria n-terminal 14.0156 14.03
+ N-methylphenylalanine METH, methylation F bacteria n-terminal 14.0156 14.03
+ N-methyltyrosine METH, methylation Y proteobacteria n-terminal 14.0156 14.03
+ N4-methylasparagine METH, methylation N cryptophyta, cyanobacteria, rhodophyta anywhere 14.0156 14.03
+ N5-methylglutamine METH, methylation Q proteobacteria, saccharomyces cerevisiae anywhere 14.0156 14.03
+ Tele-methylhistidine METH, methylation H physarum polycephalum, vertebrata anywhere 14.0156 14.03
3-hydroxyvaline HYDR, hydroxylation V anywhere 15.9949 16.0
S-(coelenterazin-3a-yl)cysteine C eukaryota anywhere 421.143 421.45
S-farnesyl cysteine FARN, prenylation C eukaryota anywhere 204.188 204.35
GPI-anchor amidated aspartate gpi-anchor D eukaryota c-terminal
Decarboxylated threonine T c-terminal -43.9898 -44.01
Dimethylation DIMETH , A, K, N, P, R, S bacillus amyloliquefaciens (strain fzb42), bacillus pumilus, bacteria, echinodermata, euglenozoa, eukaryota, homo sapiens, sipunculus nudus, vertebrata, viridiplantae 28.0314 28.0538
+ N,N-dimethylalanine METH, dimethylation A viridiplantae n-terminal 28.0313 28.06
+ N,N-dimethylserine METH, dimethylation S eukaryota n-terminal 28.0313 28.05
+ N4,N4-dimethylasparagine DIMETH, METH, dimethylation N homo sapiens anywhere 28.0313 28.06
+ N6,N6-dimethyllysine DIMETH, METH, dimethylation K bacteria, eukaryota anywhere 28.0313 28.06
+ N,N-dimethylproline DIMETP, METH, dimethylation, dimethylation of proline P echinodermata, euglenozoa, sipunculus nudus n-terminal 28.0313 28.06
+ Omega-N-methylated arginine DIMETH, METH, dimethylation R eukaryota anywhere 28.0313 28.06
+ Dimethylated arginine DIMETH, dimethylation , R bacillus amyloliquefaciens (strain fzb42), bacillus pumilus, eukaryota, vertebrata anywhere 28.0313 28.05
+ + N2,N2-dimethylarginine DIMETH, dimethylation R bacillus amyloliquefaciens (strain fzb42), bacillus pumilus n-terminal 28.0313 28.06
+ + Asymmetric dimethylarginine DIMETH, dimethylation R eukaryota anywhere 28.0313 28.05
+ + Symmetric dimethylarginine DIMETH, dimethylation R vertebrata anywhere 28.0313 28.06
1-amino-2-propanone T bacillus cereus (strain atcc 14579 / dsm 31) c-terminal -46.0055 -46.03
N6-murein peptidoglycan lysine peptidoglycan-anchor K proteobacteria anywhere
GPI-like-anchor amidated alanine gpi-anchor A c-terminal
Aspartyl isopeptide (Asn) N mammalia core 0.984016 0.98
Amidation AMID A, C, D, E, F, G, H, I, K, L, M, N, P, Q, R, S, T, V, W, Y arthropoda, conus geographus, gastropoda, metazoa, phyllomedusa sauvagei, planobispora rosea, streptomyces azureus -0.984 -0.9847
+ Arginine amide AMID, amidation R metazoa c-terminal -0.984016 -0.98
+ Alanine amide AMID, amidation A metazoa c-terminal -0.984016 -0.98
+ Serine amide AMID, amidation S metazoa, streptomyces azureus c-terminal -0.984016 -0.98
+ Tyrosine amide AMID, amidation Y metazoa c-terminal -0.984016 -0.98
+ Leucine amide AMID, amidation L metazoa c-terminal -0.984016 -0.98
+ Threonine amide AMID, amidation T metazoa c-terminal -0.984016 -0.98
+ Aspartic acid 1-amide AMID, amidation D conus geographus, phyllomedusa sauvagei c-terminal -0.984016 -0.98
+ Asparagine amide AMID, amidation N metazoa c-terminal -0.984016 -0.98
+ Cysteine amide AMID, amidation C arthropoda, gastropoda c-terminal -0.984016 -0.98
+ Glutamic acid 1-amide AMID, amidation E metazoa c-terminal -0.984016 -0.98
+ Glutamine amide AMID, amidation Q metazoa c-terminal -0.984016 -0.98
+ Glycine amide AMID, amidation G metazoa c-terminal -0.984016 -0.98
+ Histidine amide AMID, amidation H metazoa c-terminal -0.984016 -0.98
+ Isoleucine amide AMID, amidation I metazoa c-terminal -0.984016 -0.98
+ Lysine amide AMID, amidation K metazoa c-terminal -0.984016 -0.98
+ Methionine amide AMID, amidation M metazoa c-terminal -0.984016 -0.98
+ Phenylalanine amide AMID, amidation F metazoa c-terminal -0.984016 -0.98
+ Proline amide AMID, amidation P metazoa, planobispora rosea c-terminal -0.984016 -0.98
+ Tryptophan amide AMID, amidation W metazoa c-terminal -0.984016 -0.98
+ Valine amide AMID, amidation V metazoa c-terminal -0.984016 -0.98
GPI-anchor amidated serine gpi-anchor S eukaryota c-terminal
S-stearoyl cysteine lipoprotein C homo sapiens, semliki forest virus anywhere 266.261 266.46
D-alanine (Ser) d-amino acid S lactobacillus sakei l45 core -15.9949 -16.0
O-(5'-phospho-RNA)-tyrosine covalent protein-rna linkage, phosphoprotein Y viruses anywhere
Blocked amino end (Glu) E archaea, bacteria, eukaryota n-terminal
Blocked amino end (Asx) B archaea, bacteria, eukaryota n-terminal
N-pyruvate 2-iminyl-valine pyruvate V homo sapiens n-terminal 70.0055 70.05
S-(15-deoxy-Delta12,14-prostaglandin J2-9-yl)cysteine lipoprotein C mammalia anywhere 316.204 316.44
Glutathionylation GLUT C escherichia coli (strain k12), hevea brasiliensis, vertebrata 305.068 305.306
+ S-glutathionyl cysteine GLUT, glutathionylation C escherichia coli (strain k12), hevea brasiliensis, vertebrata anywhere 305.068 305.31
Deamidation DEAM N, Q arabidopsis thaliana, bacteria, vertebrata 0.984 0.9847
+ Deamidated asparagine DEAM, deamidation N arabidopsis thaliana, vertebrata anywhere 0.984016 0.98
+ Deamidated glutamine DEAM, deamidation Q bacteria, vertebrata anywhere 0.984016 0.98
Glycine radical organic radical G bacteria, chlamydomonas reinhardtii anywhere
2-oxobutanoic acid OXOB T staphylococcus epidermidis n-terminal -17.0265 -17.03
Blocked amino end (Asn) N archaea, bacteria, eukaryota n-terminal
(5S)-5-hydroxylysine HYDR, hydroxylation K metazoa anywhere 15.9949 16.0
O-UMP-tyrosine nucleotide-binding Y archaea, bacteria anywhere 306.025 306.17
O-(phosphoribosyl dephospho-coenzyme A)serine phosphoprotein S firmicutes, proteobacteria, treponema denticola anywhere 881.147 881.63
S-cysteinyl cysteine C mammalia anywhere 119.004 119.14
FMN conjugation (Cys) FMNC C arabidopsis thaliana, firmicutes, proteobacteria 456.105 456.34
+ S-4a-FMN cysteine FMNC, fmn, fmn conjugation (cys) C arabidopsis thaliana, firmicutes anywhere 456.105 456.34
+ S-6-FMN cysteine FMNC, fmn, fmn conjugation (cys) C proteobacteria anywhere 456.105 456.34
GPI-anchor amidated asparagine gpi-anchor N eukaryota c-terminal
Methionine derivative M archaea, bacteria, eukaryota
N6-lipoyllysine LIPY, lipoyl K archaea, bacteria, eukaryota anywhere 188.033 188.31
Blocked amino end (Ala) A archaea, bacteria, eukaryota n-terminal
Triiodothyronine THRN, iodination Y mammalia anywhere 469.716 469.78
D-leucine d-amino acid L gastropoda core
Hypusine HYPU, hypusine K archaea, eukaryota anywhere 87.0684 87.12
GPI-anchor amidated cysteine gpi-anchor C eukaryota c-terminal
N6-1-carboxyethyl lysine CETH K mammalia anywhere 72.0211 72.06
Iodotyrosine iodination Y mammalia anywhere 125.897 125.9
5-glutamyl 2-aminoadipic acid E archaea, deinococcus-thermus c-terminal 143.058 143.14
2-(S-cysteinyl)pyruvic acid O-phosphothioketal C bacteria anywhere 270.992 271.18
Aspartate 1-(chondroitin 4-sulfate)-ester proteoglycan D mammalia c-terminal
S-(4-hydroxycinnamyl)cysteine chromophore C proteobacteria anywhere 249.046 249.29
5-hydroxy-3-methylproline (Ile) HYDR, hydroxylation I anywhere 13.9793 13.98
O-AMP-threonine nucleotide-binding T eukaryota anywhere 329.053 329.21
Beta-methylthiolation BMTH D bacteria 45.9877 46.0869
+ 3-methylthioaspartic acid BMTH, beta-methylthiolation D bacteria anywhere 45.9877 46.09
Tele-(1,2,3-trihydroxypropan-2-yl)histidine H anywhere 90.0317 90.08
5-glutamyl polyglutamate E eukaryota anywhere
ADP-ribosylation ADP C, E, N, R, S bacteria, eukaryota, euryarchaeota, homo sapiens, mammalia, vertebrata 541.061 541.3
+ ADP-ribosylasparagine ADP, adp-ribosylation N homo sapiens anywhere 541.061 541.3
+ ADP-ribosylarginine ADP, adp-ribosylation R bacteria, eukaryota, euryarchaeota anywhere 541.061 541.3
+ ADP-ribosylserine ADP, adp-ribosylation S homo sapiens anywhere 541.061 541.3
+ ADP-ribosylcysteine ADP, adp-ribosylation C mammalia anywhere 541.061 541.3
+ PolyADP-ribosyl glutamic acid ADP, adp-ribosylation E vertebrata anywhere
Cysteine persulfide CYSP C archaea, eukaryota, proteobacteria anywhere 31.9721 32.06
Lactic acid S staphylococcus epidermidis n-terminal -15.0109 -15.01
2,3-didehydrotyrosine Y cnidaria core -2.01565 -2.02
D-phenylalanine d-amino acid F arthropoda, mollusca core
Myristoylation MYRI G, K eukaryota 210.198 210.36
+ N-myristoyl glycine MYRI, myristate, myristoylation G eukaryota n-terminal 210.198 210.36
+ N6-myristoyl lysine MYRI, myristate, myristoylation K eukaryota anywhere 210.198 210.36
2'-methylsulfonyltryptophan METH W amanita virosa anywhere 77.9775 78.09
Deamidation followed by a methylation DEAME Q bacteria 14.9997 15.01
+ Glutamate methyl ester (Gln) DEAME, deamidation followed by a methylation, methyl ester Q bacteria anywhere 14.9997 15.01
Cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester CHDH, lipoprotein D viridiplantae anywhere 294.183 294.39
3-oxoalanine (Ser) OXOAS S homo sapiens, proteobacteria anywhere -2.01565 -2.02
4-hydroxyglutamate HYDR, hydroxylation E streptomyces actuosus anywhere 15.9949 16.0
N-palmitoyl glycine palmitate G bos taurus n-terminal 238.23 238.41
2,3-didehydrobutyrine DHB T firmicutes core -18.0106 -18.02
O-(pantetheine 4'-phosphoryl)serine PPAN, phosphopantetheine S anywhere 340.086 340.33
Diphthamide DIPH H archaea, eukaryota anywhere 143.118 143.21
Blocked amino end (Asp) D archaea, bacteria, eukaryota n-terminal
D-valine d-amino acid V gastropoda core
(3R,4R)-3,4-dihydroxyproline HYDR, hydroxylation P amanita virosa anywhere 31.9898 32.0
Blocked amino end (Arg) R archaea, bacteria, eukaryota n-terminal
Acetylation ACET A, C, D, E, G, K, M, P, R, S, T, V, Y archaea, bacteria, chlamydomonas reinhardtii, eukaryota, euryarchaeota, homo sapiens, mammalia, metazoa, micrococcus luteus, oncorhynchus keta, proteobacteria, sulfolobus solfataricus, vertebrata, viridiplantae 42.0106 42.0373
+ N-acetylcysteine ACET, acetylation C euryarchaeota, vertebrata n-terminal 42.0106 42.04
+ N-acetylthreonine ACET, acetylation T eukaryota n-terminal 42.0106 42.04
+ O-acetylserine ACET, acetylation S homo sapiens anywhere 42.0106 42.04
+ N-acetyltyrosine ACET, acetylation Y oncorhynchus keta n-terminal 42.0106 42.04
+ N-acetylmethionine ACET, acetylation M eukaryota, micrococcus luteus, sulfolobus solfataricus n-terminal 42.0106 42.04
+ N-acetylglycine ACET, acetylation G eukaryota n-terminal 42.0106 42.04
+ N-acetylproline ACET, acetylation P mammalia, viridiplantae n-terminal 42.0106 42.04
+ O-acetylthreonine ACET, acetylation T homo sapiens anywhere 42.0106 42.04
+ N-acetylalanine ACET, acetylation A eukaryota, proteobacteria n-terminal 42.0106 42.04
+ N2-acetylarginine ACET, acetylation R viridiplantae n-terminal 42.0106 42.04
+ N-acetylaspartate ACET, acetylation D eukaryota n-terminal 42.0106 42.04
+ N-acetylglutamate ACET, acetylation E n-terminal 42.0106 42.04
+ N6-acetyllysine ACET, acetylation K archaea, bacteria, eukaryota anywhere 42.0106 42.04
+ N-acetylserine ACET, acetylation S archaea, bacteria, eukaryota n-terminal 42.0106 42.04
+ N-acetylvaline ACET, acetylation V chlamydomonas reinhardtii, metazoa n-terminal 42.0106 42.04
2,3-didehydroalanine (Cys) C saccharomyces cerevisiae core -33.9877 -34.08
N-carbamoylalanine A ectothiorhodospira mobilis n-terminal 43.0058 43.02
2',4',5'-topaquinone TOPA, tpq Y bacteria, eukaryota anywhere 29.9742 29.98
Cysteine sulfinic acid (-SO2H) CSIA, oxidation C bacteria, mammalia anywhere 31.9898 32.0
N-(12-oxomyristoyl)cysteine myristate C n-terminal 224.178 224.34
3-hydroxyhistidine HYDR, hydroxylation H metazoa anywhere 15.9949 16.0
Lysino-D-alanine (Lys) K fungi anywhere 87.032 87.08
D-tryptophan d-amino acid W gastropoda core
L-allo-isoleucine I core
Tryptophan derivative W archaea, bacteria, eukaryota
D-serine (Ser) d-amino acid S agelenopsis aperta, octopus minor core
7'-hydroxytryptophan HYDR, hydroxylation W perna viridis anywhere 15.9949 16.0
(3R,4S)-3,4-dihydroxyproline HYDR, hydroxylation P mytilus edulis anywhere 31.9898 32.0
Trimethylation TRIMETH A, K, S archaea, bacteria, cylindrotheca fusiformis, eukaryota, oryctolagus cuniculus, proteobacteria, tetrahymena pyriformis 42.0471 42.0807
+ N,N,N-trimethylserine METH, trimethylation S eukaryota n-terminal 43.0542 43.09
+ N6,N6,N6-trimethyl-5-hydroxylysine HYDR, METH, TRIMETK, hydroxylation, trimethylation K cylindrotheca fusiformis anywhere 58.0419 58.08
+ N6,N6,N6-trimethyllysine METH, TRIMETH, trimethylation K bacteria, eukaryota anywhere 42.047 42.08
+ N6-methylated lysine METH, TRIMETH, trimethylation K archaea, bacteria, eukaryota anywhere 42.047 42.08
+ N,N,N-trimethylalanine METH, TRIMETH, trimethylation A oryctolagus cuniculus, proteobacteria, tetrahymena pyriformis n-terminal 42.047 42.08
FMN conjugation (Ser/Thr) FMN S, T bacteria, proteobacteria 438.094 438.33
+ FMN phosphoryl serine fmn, fmn conjugation (ser/thr) S proteobacteria anywhere 438.094 438.33
+ FMN phosphoryl threonine fmn, fmn conjugation (ser/thr) T bacteria anywhere 438.094 438.33
Hydroxylation HYDR D, K, N, P, R, V, W, Y actinobacteria, eukaryota, gastropoda, hydrogenophaga pseudoflava, metazoa, phanerochaete chrysosporium, proteobacteria, vertebrata 15.9949 15.9994
+ D-4-hydroxyvaline HYDR, d-amino acid, hydroxylation V gastropoda core 15.9949 16.0
+ 3-hydroxyaspartate HYDR, hydroxylation D vertebrata anywhere 15.9949 16.0
+ 3',4'-dihydroxyphenylalanine HYDR, hydroxylation Y actinobacteria, metazoa anywhere 15.9949 16.0
+ 5-hydroxylysine HYDR, hydroxylation K metazoa anywhere 15.9949 16.0
+ 4-hydroxyproline HYDR, hydroxylation P eukaryota anywhere 15.9949 16.0
+ 3-hydroxytryptophan HYDR, hydroxylation W phanerochaete chrysosporium, proteobacteria anywhere 15.9949 16.0
+ Hydroxyproline HYDR, hydroxylation P eukaryota anywhere 15.9949 16.0
+ 3-hydroxyproline HYDR, hydroxylation P metazoa anywhere 15.9949 16.0
+ 3-hydroxyasparagine HYDR, hydroxylation N vertebrata anywhere 15.9949 16.0
+ 4-hydroxyarginine HYDR, hydroxylation R hydrogenophaga pseudoflava anywhere 15.9949 16.0
D-alanine (Ala) d-amino acid A amphibia core
N6-(pyridoxal phosphate)lysine PLP, pyridoxal phosphate K archaea, bacteria, eukaryota anywhere 229.014 229.13
O-(5'-phospho-RNA)-serine covalent protein-rna linkage, phosphoprotein S chordata, viruses anywhere
Aspartyl aldehyde D cryptophyta, euglenozoa, rhodophyta, stramenopiles, viridiplantae anywhere -15.9949 -16.0
Pyrrolidone carboxylic acid PYRR, pyrrolidone carboxylic acid Q bacteria, eukaryota, euryarchaeota n-terminal -17.0265 -17.03
O-(2-cholinephosphoryl)serine phosphoprotein S eukaryota, neisseriales anywhere 253.095 253.21
Pentaglycyl murein peptidoglycan amidated threonine peptidoglycan-anchor T bacteria anywhere
5'-chlorotryptophan W anywhere 33.961 34.45
N-pyruvate 2-iminyl-cysteine pyruvate C enterobacteriaceae n-terminal 70.0055 70.05
Threonine methyl ester methyl ester T c-terminal 14.0156 14.03
Pyruvic acid (Cys) PYRUC, pyruvate C enterobacteria phage mu, firmicutes n-terminal -33.0037 -33.1
N-acetylisoleucine ACET, acetylation I rattus norvegicus n-terminal 42.0106 42.04
Glycyl adenylate nucleotide-binding G eukaryota, proteobacteria c-terminal 329.053 329.21
N6-(ADP-ribosyl)lysine ADP, adp-ribosylation K mus musculus anywhere 541.061 541.3
S-(dipyrrolylmethanemethyl)cysteine C archaea, bacteria, eukaryota anywhere 418.138 418.4
Allysine ALLYS K ephydatia muelleri, vertebrata anywhere -1.03163 -1.03
Methionine sulfoxide oxidation M eukaryota anywhere 15.9949 16.0
(3R,4S)-4-hydroxyisoleucine HYDR, hydroxylation I amanita phalloides anywhere 15.9949 16.0
S-selanylcysteine selenium C escherichia coli anywhere 79.9165 78.96
Gamma-carboxyglutamic acid GGLU E mollusca, vertebrata 43.9898 44.0098
+ 4-carboxyglutamate GGLU, gamma-carboxyglutamic acid E mollusca, vertebrata anywhere 43.9898 44.01
3'-nitrotyrosine Y trametes maxima core 44.9851 45.0
N2-succinyltryptophan W bacillus subtilis n-terminal 100.016 100.07
O-AMP-tyrosine nucleotide-binding Y archaea, bacteria, eukaryota anywhere 329.053 329.21
Blocked amino end (Cys) C archaea, bacteria, eukaryota n-terminal
GPI-like-anchor amidated aspartate gpi-anchor D dictyostelium discoideum c-terminal
O-(5'-phospho-DNA)-serine covalent protein-dna linkage, phosphoprotein S viruses anywhere
Formylation FORM G, K, M apis mellifera, bacteria, eukaryota 27.9949 28.0104
+ N-formylglycine FORM, formylation G apis mellifera n-terminal 27.9949 28.01
+ N6-formyllysine FORM, formylation K apis mellifera anywhere 27.9949 28.01
+ N-formylmethionine FORM, formylation M bacteria, eukaryota n-terminal 27.9949 28.01
Diiodotyrosine iodination Y mammalia anywhere 251.793 251.79
S-bacillithiol cysteine disulfide C bacteria anywhere 396.084 396.37
Serine microcin E492 siderophore ester S klebsiella pneumoniae c-terminal 831.197 831.69
3-phenyllactic acid FLAC F cnidaria n-terminal 0.984016 0.98
Isoleucine derivative I archaea, bacteria, eukaryota
Phosphatidylethanolamine amidated glycine PE, lipoprotein G eukaryota c-terminal 699.52 699.98
CysO-cysteine adduct G bacteria c-terminal
Blocked amino end (Ile) I archaea, bacteria, eukaryota n-terminal
Blocked amino end (Gln) Q archaea, bacteria, eukaryota n-terminal
S-12-hydroxyfarnesyl cysteine FAR0, prenylation C tremella mesenterica anywhere 220.183 220.35
Glutamine derivative Q archaea, bacteria, eukaryota
Citrullination CITR R vertebrata 0.984028 0.98476
+ Citrulline CITR, citrullination R vertebrata anywhere 0.984016 0.98
GPI-like-anchor amidated glycine gpi-anchor G dictyostelium discoideum c-terminal
Blocked carboxyl end (Arg) R archaea, bacteria, eukaryota c-terminal
Cysteine methyl disulfide C bacteria anywhere 45.9877 46.09
Blocked amino end (Leu) L archaea, bacteria, eukaryota n-terminal
(E)-2,3-didehydrobutyrine T core -18.0106 -18.02
(Z)-2,3-didehydrobutyrine T firmicutes core -18.0106 -18.02
O-(sn-1-glycerophosphoryl)serine S proteobacteria anywhere 154.003 154.06
N6-biotinyllysine BIOT, biotin K archaea, bacteria, eukaryota anywhere 226.078 226.3
Blocked carboxyl end (His) H archaea, bacteria, eukaryota c-terminal
Sumoylation SUMO K eukaryota anywhere
Ubiquitination UBIQ, ubiquitylation K eukaryota anywhere
Pupylation PUP K archaea, bacteria anywhere
Glycosylation GLCN N, S, T, W eukaryota anywhere
+ O-Glycosylation GLCN, Glycosylation S, T eukaryota anywhere
+ + O-GlcNAc Serine GLCN, Glycosylation, O-Glycosylation S eukaryota anywhere 203.079 203.195
+ + O-GlcNAc Threonine GLCN, Glycosylation, O-Glycosylation T eukaryota anywhere 203.079 203.195
+ + O-GalNAc Serine GLCN, Glycosylation, O-Glycosylation S anywhere 203.079 203.195
+ + O-GalNAc Threonine GLCN, Glycosylation, O-Glycosylation T 203.079 203.195
+ N-Glycosylation GLCN, Glycosylation N anywhere
+ C-Glycosylation GLCN, Glycosylation W anywhere
N6-crotonyl-L-lysine N6-crotonyllysine K vertebrata anywhere 68.0262 68.07
None anywhere