Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants


Experiment Name
Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants
Citation
Iwai LK,Payne LS,Luczynski MT,Chang F,Xu H,Clinton RW,Paul A,Esposito EA,Gridley S,Leitinger B,Naegle KM,Huang PH. The Biochemical journal. 2013-August. Vol 454. 501-13. [pubmed]
Description
HEK293 cells expressing DDR2 were stimulated with soluble collagen I and phosphorylation was quantitatively profiled across time.
Conditions
Cell
HEK 293
Stimulus
Collagen I
Date Loaded
September 08 2014

Experiment Data Summary

Proteins
305
Measured Peptides
416
Modification Sites
450
Rejected Peptides
129
By Residue By Modification Type By Species
S 337
Y 80
T 33
Phosphorylation 450
homo sapiens 450

Peptide Sequence Profile